Objective: To compare the data of corneal thickness measured with Orbscan Topography System (ORB) and DGH-4000 ultrasonic pachymetry. Methods: Measurement was assessed in 74 eyes using both ORB and UP. Using Software of SPSS, corneal thickness was compared using paired samples t-test. The relationship between the devices was assessed by analysis of regression (ANOR). Results: In the measurement, the mean values of corneal thickness from different instruments were significantly different (P