National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81573193]; Hunan Provincial Innovation Foundation For Postgraduate [CX2018B629]; Natural Science Foundation of Hunan ProvinceNatural Science Foundation of Hunan Province [2020JJ4082]
机构署名:
本校为第一且通讯机构
院系归属:
公共卫生学院
摘要:
Beryllium and its compounds are systemic toxicants that mainly accumulate in the lungs. As a regulator of gene expression, microRNAs (miRNAs) were involved in some lung diseases. This study aimed to analyze the levels of some inflammatory cytokine and the differential expressions of miRNAs in human bronchial epithelial cells (16HBE) induced by beryllium sulfate (BeSO4) and to further explore the biological functions of differentially expressed miRNAs. The profile of miRNAs in 16HBE cells was detected using the high-throughput sequencing between...