The patch clamp recording techniques is an advanced electrophysiological technique, which has been widely used for research in the life science research field. It vas applied to studying on the electrophysiological character of ion channels in atherosclerotic vascular smooth muscle cells. It has been found that apoptosis of vascular smooth muscle cells vas relate with increase of K+ channel action. Large-conductance BKCa, channel plays a important role in development of atherosclerosis. Some drugs may affect ion channels in atherosclerotic vascular smooth muscle cells. The patch clamp techniqu...