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Promoter regions of sxtA and sxtG reveal relationship between saxitoxin biosynthesis and photosynthesis in toxic Alexandrium catenella

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成果类型:
期刊论文
作者:
Kim, Han-Sol;Bui, Quynh Thi Nhu;Shin, Jeongmin;Wang, Hui*;Ki, Jang-Seu
通讯作者:
Wang, Hui;Ki, JS;Wang, H
作者机构:
[Wang, Hui; Kim, Han-Sol; Shin, Jeongmin; Ki, Jang-Seu; Bui, Quynh Thi Nhu; Ki, JS] Sangmyung Univ, Dept Biotechnol, Seoul 03016, South Korea.
[Wang, Hui] Univ South China, Sch Publ Hlth, Hunan Prov Key Lab Typ Environm Pollut & Hlth Haza, Hengyang 421001, Peoples R China.
通讯机构:
[Wang, H; Ki, JS ] S
[Wang, H ] U
Sangmyung Univ, Dept Biotechnol, Seoul 03016, South Korea.
Univ South China, Sch Publ Hlth, Hunan Prov Key Lab Typ Environm Pollut & Hlth Haza, Hengyang 421001, Peoples R China.
语种:
英文
关键词:
STX biosynthesis gene (sxt);Promoter;Untranslated region (UTR);Transcriptional regulation;Alexandrium catenella
期刊:
Journal of Applied Phycology
ISSN:
0921-8971
年:
2024
页码:
1-15
基金类别:
This work was supported by the National Research Foundation of Korea (NRF) under grants (2020R1A2C2013373 and 2022R1A6A3A13071839) in part by the MSIT (Ministry of Science and ICT) and by the project titled 'Development of hull adherent organism management technology (20210651)' funded by the Ministry of Oceans and Fisheries, Korea.
机构署名:
本校为第一且通讯机构
院系归属:
公共卫生学院
摘要:
The marine dinoflagellate Alexandrium catenella (Group I) produces saxitoxins (STXs) in marine environments, causing paralytic shellfish poisoning (PSP). The toxins are synthesized by STXs biosynthesis genes (sxt); of them, sxtA and sxtG are considered the most essential. The promoter region and 3'-untranslated region (3'-UTR) are known to regulate gene transcription; however, they have not been sufficiently elucidated in the sxt genes. Herein, we determined and characterized the genomic DNA sequence of the proximal regions of sxtA and sxtG in A. catenella. The promoter regions of sxtA and sxt...

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