期刊论文

Study on the volume and position of target volume in different phases under different breathing modes based on four-dimensional CT images

中文

现代肿瘤医学

1672-4992

2022

30

20

3763-3768

10.3969/j.issn.1672-4992.2022.20.025

NCC2018B63:国家癌症中心攀登基金 202109031926:湖南省卫生健康委科研计划项目 CX2018B58:湖南省研究生科研创新项目

本校为第一机构

目的:基于四维CT图像研究不同呼吸模式下适用于呼吸门控治疗的时相。方法:使用CIRS呼吸运动模体,驱动模体中间植入金标的小球(靶区)分别以标准正弦、呼气末停滞、呼气时长大于吸气时长三种模式运动,并进行分成10个均匀时相的4DCT扫描,分析各时相中靶区体积与金标位置。结果:三种呼吸模式下各时相靶区体积变化率与运动幅度有强相关性,40%、50%和60%时相靶区体积变化率较其他时相上更小;用金标判断运动幅度平均误差为8.6%;用大体肿瘤靶区(gross tumor volume, GTV)质心判断运动幅度平均误差为34.6%。三种模式在40%~60%时相金标平均偏移率均

Objective:To study the phases suitable for respiratory-gated therapy in different respiratory modes based on four-dimensional CT images.Methods:The CIRS breathing motion phantom was used to drive the gold-labeled ball(target area) in the middle of the phantom to move in three modes: Standard sine, end-expiratory stagnation, and expiratory time longer than inspiratory time, and divided into ten uniform phases.The 4 DCT scan of the uniform phase was used to analyze the volume of the target volume and the position of the gold standard in each phase.Results:The volume change rate of the target vol...