The chromosome damage was examined by using peripheral blood micronucleus test performed by acridine orange supravital staining and bone morrow chromosome aberration assay after rats were exposed to cigarette smoke for ten months.The incidence of structural chromosome aberrations from rats exposed to cigarette smoking is 3.36%,which is significantly greater than that of control rats (1.73%).The frequencies of micronucleuted reticulocytes(MNRETS)in experimental group were also found to be significantly greater than that in control group.The former is 1.41%,and the latter ...
