Methanol and salicylic acid is a hot drug chemical synthesis in high yield synthesis methylis salicylas. In this paper, it studies dosage of sodium bisulfate catalyst, methanol dosage and response time, with admixture of select catalytic synthesis of methyl salicylate and other factors on the yield effects under conditions of water combined with sodium bisulfate catalyst, methanol and salicylic acid by high-yield synthesis of methyl salicylate. Experimental results demonstrate that Ester yields was upto 77.0% for the best conditions, when metha...