[Li, Jie; Chen, Gen; Xie, Xi] Univ South China, Inst Pharm & Pharmacol, Hengyang, Hunan, Peoples R China.

[Chen, Xiao-Lan; Li, Jie; Lin, Jie] Xiangnan Univ, Peoples Hosp Chenzhou 1, Chenzhou 423000, Hunan, Peoples R China.

[Xu, Cang-Bao] Xian Med Univ, Inst Basic & Translat Med, Shaanxi Key Lab Ischem Cardiovasc Dis, Xian, Shaanxi, Peoples R China.

[Luo, Hong-Li] Southwest Med Univ, Affiliated Hosp, Dept Pharm, Luzhou, Sichuan, Peoples R China.

[Li, Jie] X

Xiangnan Univ, Peoples Hosp Chenzhou 1, Chenzhou 423000, Hunan, Peoples R China.

calcium activated potassium channel;interleukin 1beta;KCa2.3 protein;KCa3.1 protein;low density lipoprotein;messenger RNA;mitogen activated protein kinase p38;monoclonal antibody;toll like receptor 4;toll like receptor 4 monoclonal antibody;toll like receptor antagonist;transcription factor RelA;tumor necrosis factor;unclassified drug;IL1B protein, mouse;interleukin 1beta;intermediate conductance calcium activated potassium channel;Kcnn3 protein, mouse;Kcnn4 protein, mouse;low density lipoprotein;mitogen activated protein kinase p38;monoclonal antibody;oxidized low density lipoprotein;Rela protein, mouse;small conductance calcium activated potassium channel;Tlr4 protein, mouse;Tnf protein, mouse;toll like receptor 4;transcription factor RelA;tumor necrosis factor;animal experiment;animal model;animal tissue;Article;blood vessel function;controlled study;down regulation;endothelium dependent vasodilation;enzyme linked immunosorbent assay;experimental cardiovascular disease;gene expression;mesenteric artery;minimally modified low density lipoprotein endothelium dependent vasodilation dysfunction;minimally modified low density lipoprotein endothelium dependent vasodilation dysfunction;mouse;nonhuman;priority journal;protein blood level;reverse transcription polymerase chain reaction;TLR signaling;upregulation;vascular disease;vasodilatation;Western blotting;animal;blood;drug effect;female;genetics;immunology;Institute for Cancer Research mouse;male;mesenteric artery;metabolism;phosphorylation;signal transduction;vascular endothelium;vasodilatation;Animals;Antibodies, Monoclonal;Endothelium, Vascular;Female;Interleukin-1beta;Intermediate-Conductance Calcium-Activated Potassium Channels;Lipoproteins, LDL;Male;Mesenteric Arteries;Mice, Inbred ICR;p38 Mitogen-Activated Protein Kinases;Phosphorylation;Signal Transduction;Small-Conductance Calcium-Activated Potassium Channels;Toll-Like Receptor 4;Transcription Factor RelA;Tumor Necrosis Factor-alpha;Vasodilation

药学与生物科学学院