Non-coding RNAs: Key regulators of aerobic glycolysis in breast cancer

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作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Xia, Min;Feng, Shujun;Chen, Zuyao;Wen, Gebo;Zu, Xuyu*;...

通讯作者：

Zu, Xuyu;Zhong, Jing

作者机构：

[Chen, Zuyao; Wen, Gebo; Zhong, Jing; Zu, Xuyu; Zhong, J; Xia, Min] Univ South China, Inst Clin Med, Affiliated Hosp 1, Hengyang 421001, Hunan, Peoples R China.

[Zhong, Jing; Zu, Xuyu] Univ South China, Canc Res Inst, Affiliated Hosp 1, Hengyang 421001, Hunan, Peoples R China.

[Wen, Gebo; Xia, Min] Univ South China, Dept Endocrinol & Metab, Affiliated Hosp 1, Hengyang 421001, Hunan, Peoples R China.

[Feng, Shujun] Univ South China, Canc Res Inst, Hunan Prov Key Lab Tumor Cellular & Mol Pathol, Hengyang, Hunan, Peoples R China.

通讯机构：

[Zu, XY; Zhong, J] U

Univ South China, Inst Clin Med, Affiliated Hosp 1, Hengyang 421001, Hunan, Peoples R China.

语种：

英文

关键词：

circular ribonucleic acid;microRNA;untranslated RNA;glucose;long untranslated RNA;microRNA;untranslated RNA;aerobic glycolysis;breast cancer;down regulation;gene expression;glycolysis;human;oncogene;Review;tumor suppressor gene;upregulation;aerobic metabolism;breast tumor;female;gene expression regulation;glycolysis;metabolism;neoplasm;signal transduction;tumor cell line;Aerobiosis;Breast Neoplasms;Cell Line, Tumor;Female;Gene Expression Regulation, Neoplastic;Genes, Tumor Suppressor;Glucose;Glycolysis;Humans;MicroRNAs;Neoplasms;Oncogenes;RNA, Circular;RNA, Long Noncoding;RNA, Untranslated;Signal Transduction

期刊：

Life Sciences

ISSN：

0024-3205

年：

2020

卷：

250

页码：

117579

DOI：

10.1016/j.lfs.2020.117579

基金类别：

This work was supported by the grants from the National Natural Science Foundation of China (Nos. 81773294 and 81472608), the Natural Science Foundation of Hunan Province (No. 2019JJ20014), the Major Program of National Health and Family Planning Commission of Hunan (A2017013), and the Chuanshan Talent Project of the University of South China (No. CS2018-3-35). This work was supported by the grants from the National Natural Science Foundation of China (Nos. 81773294 and 81472608 ), the Natural Science Foundation of Hunan Province (No. 2019JJ20014 ), the Major Program of National Health and Family Planning Commission of Hunan ( A2017013 ), and the Chuanshan Talent Project of the University of South China (No. CS2018-3-35 ).

机构署名：

本校为第一且通讯机构

院系归属：

医学院

摘要：

Although extensive research progress has been made in breast cancer in recent years, yet the morbidity and mortality rates of breast cancer are rising, making it the major disease that endangers women's health. Energy metabolism reprogramming is featured by a state termed “aerobic glycolysis” or the Warburg effect that glycolysis is preferred even under aerobic conditions in neoplastic diseases. Widely acknowledged as an emerging hallmark in cancers, this metabolic switch shows a sophisticated role in the pathogenesis of breast cancer. The re...

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Non-coding RNAs: Key regulators of aerobic glycolysis in breast cancer

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