Hemin protects against hippocampal damage following orthotopic autologous liver transplantation in adult rats

首页 > 成果 > 详情

认领

导出

下载 Link by DOI

反馈

作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Wang, Yiheng;Xia, Hua;Yu, Xiaofang;Lu, Tingting;Chi, Xinjin;...

通讯作者：

Cai, Jun

作者机构：

[Xia, Hua; Cai, Jun; Chi, Xinjin; Wang, Yiheng] Sun Yat Sen Univ, Affiliated Hosp 3, Dept Anesthesiol, Guangzhou 510630, Guangdong, Peoples R China.

[Wang, Yiheng] Univ South China, Affiliated Hosp 1, Dept Anesthesiol, Hengyang 421000, Hunan, Peoples R China.

[Xia, Hua] Luzhou Med Sch, Affiliated Hosp, Dept Anesthesiol, Luzhou 646000, Sichuan Provinc, Peoples R China.

[Yu, Xiaofang] Fujian Prov Hosp, Dept Anesthesiol, Fuzhou 350000, Fujian Province, Peoples R China.

[Lu, Tingting] Sun Yat Sen Univ, Affiliated Hosp 3, Dept Neurol, Guangzhou 510630, Guangdong, Peoples R China.

通讯机构：

[Cai, Jun] S

Sun Yat Sen Univ, Affiliated Hosp 3, Dept Anesthesiol, 600 Tianhe Rd, Guangzhou 510630, Guangdong, Peoples R China.

语种：

英文

关键词：

HO-1;Hemin;Hippocampus;Liver transplantation;OALT

期刊：

Life Sciences

ISSN：

0024-3205

年：

2015

卷：

135

页码：

27-34

DOI：

10.1016/j.lfs.2015.05.021

基金类别：

Science and Technology Planning Project of Guangdong Province, P. R. China [2009B030801125]

机构署名：

本校为其他机构

院系归属：

医学院

摘要：

Aims: Induction of heme oxygenase-1 (HO-1) has been widely accepted to be neuro-protective. This study aimed to examine whether hemin (a HO-1 inducer) attenuates neuronal damage in the hippocampus induced by orthotopic autologous liver transplantation (OALT) in adult rats. Main methods: Rats were randomly allocated into four groups (n = 8 each): (i) Sham control group; (ii) OALT model group; (iii) Hemin + OALT group, with intra-peritoneal (i.p.) injection of hemin (5 mg/kg) 24 hours (h) before the OALT; and (iv) ZnPP (a HO-1 inhibitor) + OALT group, with i.p. injection of ZnPP (32 mg/kg) 24 h ...

反馈

产权有误：本人成果被他人认领

数据有误：数据基本信息有误

归属有误：成果的院系归属、机构署名归属有误

其他原因：

验证码：

看不清楚，换一个

确定

取消

成果认领

标题：

用户	作者	通讯作者	--
	请选择	请选择	--

确定

取消

Hemin protects against hippocampal damage following orthotopic autologous liver transplantation in adult rats

反馈

成果认领

提示

该栏目需要登录且有访问权限才可以访问