期刊论文

Wu YiMou

英文

中国科学:生命科学(英文版)

1674-7305

2013

56

2

174-180

10.1007/s11427-012-4434-4

This work was supported by the Foundation of Hunan Province Science and Technology Department, China （2010FJ2008, 2012TT2006）, the Natural Science Foundation of Hunan Province Science and Technology Department, China （11JJ9023） and the Foundation of Hunan Province Education Department, China （ l l B107）.

本校为第一且通讯机构

Syphilis is a multistage, sexually transmitted disease caused by the spirochete, Treponema pallidum (Tp). A significantly high incidence of syphilis has been reported in several countries, including China, and there is an urgent need for the development of efficacious vaccines against syphilis. DNA vaccines are a major breakthrough in the field of vaccination with several advantages over traditional vaccines. Animal model studies of Tp DNA vaccines have not been reported elsewhere but our previous reports describe the development of a single-ge...