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New insights on the role of microRNAs in retinal Müller glial cell function

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成果类型:
期刊论文
作者:
Jiang, Weijie;He, Siqi;Liu, Logen;Meng, Xia;Lu, Jing;...
通讯作者:
Xiao, QG;Qi, L;Zhang, J
作者机构:
[He, Siqi; Jiang, Weijie; Liu, Logen; Zhang, Jia] Univ South China, Affiliated Hosp 2, Hengyang Med Sch, Clin Res Ctr, Hengyang, Hunan, Peoples R China.
[Chen, Tuo; Li, Juan; Meng, Xia; Xiao, Qiguo; Lu, Jing] Univ South China, Affiliated Hosp 2, Hengyang Med Sch, Dept Gastroenterol, Hengyang, Hunan, Peoples R China.
[Xu, Ying] Jinan Univ, Minist Educ, Guangdong Hong Kong Macau Inst Cent Nervous Syst, Key Lab Cent Nervous Syst Regenerat, Guangzhou, Peoples R China.
[Qi, Ling] Guangzhou Med Univ, Affiliated Hosp 6, Qingyuan Peoples Hosp, Inst Digest Dis, Qingyuan, Peoples R China.
[Zhang, Jia] Univ South China, Affiliated Hosp 2, Hengyang 421001, Hunan, Peoples R China.
通讯机构:
[Xiao, QG ; Zhang, J ] U
[Qi, L ] G
Univ South China, Affiliated Hosp 2, Hengyang Med Sch, Dept Gastroenterol, Hengyang, Hunan, Peoples R China.
Guangzhou Med Univ, Affiliated Hosp 6, Qingyuan Peoples Hosp, Inst Digest Dis, Qingyuan, Peoples R China.
Univ South China, Affiliated Hosp 2, Hengyang 421001, Hunan, Peoples R China.
语种:
英文
关键词:
immunology;inflammation;retina
期刊:
BRITISH JOURNAL OF OPHTHALMOLOGY
ISSN:
0007-1161
年:
2024
卷:
108
期:
3
页码:
329-335
基金类别:
This work was supported by Guangdong Basic and Applied Basic Research Foundation (grant number 2020A1515110421), National Natural Science Foundation of China (grant number 82101165), Natural Science Foundation of Hunan Province (grant number 2022JJ30522).
机构署名:
本校为第一且通讯机构
摘要:
MicroRNAs belong to the family of non-coding RNAs that participate in cell proliferation, cell death and development. The Müller glial cells are the inherent and specific neuroglia cells in the retinal organisation and play significant roles in retinal neuroprotection, organisational maintenance, inflammation and immunity, regeneration, and the occurrence and development of retinal diseases. However, only a few studies report the underlying mechanism of how miRNAs drive the function of Müller glial cells in the development of retinal diseases...

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