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Rapid eye movement sleep deprivation does not affect fear memory reconsolidation in rats

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成果类型:
期刊论文
作者:
Tian, Shaowen*;Huang, Fulian;Li, Peng;Ouyang, Xinping;Li, Zengbang;...
通讯作者:
Tian, Shaowen
作者机构:
[Huang, Fulian; Tian, Shaowen; Yang, Yufeng; Deng, Haifeng; Li, Zengbang; Ouyang, Xinping] Univ S China, Coll Med, Dept Physiol, Hengyang 421001, Hunan, Peoples R China.
[Li, Peng] Univ S China, Coll Life Sci & Technol, Dept Biol, Hengyang 421001, Hunan, Peoples R China.
通讯机构:
[Tian, Shaowen] U
Univ S China, Coll Med, Dept Physiol, Hengyang 421001, Hunan, Peoples R China.
语种:
英文
关键词:
Sleep;Rapid eye movement sleep deprivation;Fear memory;Reconsolidation;Rats
期刊:
Neuroscience Letters
ISSN:
0304-3940
年:
2009
卷:
463
期:
1
页码:
74-77
基金类别:
National Natural Science Foundation of China [30770689]; Hunan Provincial Education Department [05B045]; National Basic Research Program of China [2002CB410803-04]; University of South China Doctor Foundation [5-03-XJQ-03-041]
机构署名:
本校为第一且通讯机构
院系归属:
医学院
药学与生物科学学院
摘要:
There is increasing evidence that sleep may be involved in memory consolidation. However, there remain comparatively few studies that have explored the relationship between sleep and memory reconsolidation. At present study, we tested the effects of rapid eye movement sleep deprivation (RSD) on the reconsolidation of cued (experiment 1) and contextual (experiment 2) fear memory in rats. Behaviour procedure involved four training phases: habituation, fear conditioning, reactivation and test. Rats were subjected to 6h RSD starting either immediately after reactivation or 6h later. The control ra...

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