Project of Hengyang Science and Technology Bureau [2018KJ111, 2016KF14]; Hunan Key Laboratory of Typical Environmental Pollution and Health Hazards, School of Public Health, Hengyang Medical School, University of South China [2019TP1027]; Key Laboratory of Ecological Environment and Critical Human Diseases Prevention of Hunan Province Department of Education, School of Basic Medical Sciences, Hengyang Medical School, University of South China [2019-379]; Project of College Students' Innovative Entrepreneurial Training of Hunan Province [S202310555206]