期刊论文

中文

化工中间体(市场快讯版)

1672-8114

2012

11

31-33

本校为第一机构

以对甲氧基苯甲醛和3,5-二甲氧基苯甲醛分别与常见的几种脱甲基试剂反应,探讨甲醚芳醛类化合物的最佳脱甲基体系和条件。结果显示,脱单甲氧基芳醛类化合物以吡啶盐酸盐反应收率高且后处理最简单,二甲醚芳香醛脱甲基方法中碘化铝方法脱甲基最好,收率高,处理简单且经济实惠。

Several different demethylation methods including 48% hydrogen bromide,pyridine hydrochloride,boron tribromide,aluminum tri-iodide were compared to gain the best demethylation conditions using p-methoxybenzaldehyde and 3,5-dimethoxybenzaldehyde as model methoxy-substituted aromatic aldehydes.Results shows pyridine hydrochloride is the best substrate to de-mono-methoxy group,and aluminum iodid...