期刊论文

Zhang, Liang

英文

Biochemical and Biophysical Research Communications

0006-291X

2009

379

2

277-282

10.1016/j.bbrc.2008.12.038

The authors are indebted to Drs. Tie-Bang Kang (State Key Laboratory of Oncology in Southern China and Departments of Experimental Research, Sun Yat-sen University Cancer Center, Guangzhou) and Dr. Dana Lawrence (Palmer College of Chiropractic, Davenport, IA) for their valuable help in the preparation of the manuscript. This work was supported by grants from the National Major Basic Research Program of China (973 Program References No. 2006CB503808), the National Natural Science Foundation of China (30770868) and the Educational Department of Hunan Province, China (06C099); L.Z. is supported by National Institutes Health, USA (AG21999-7).

本校为其他机构

Proliferation of vascular smooth muscle cells (VSMCs) contributes to the development of various cardiovascular diseases. Curcumin, extracted from Curcumae longae, has been shown a variety of beneficial effects on human health, including anti-atherosclerosis by mechanisms poorly understood. In the present study, we attempted to investigate whether curcumin has any effect on VSMCs proliferation and the potential mechanisms involved. Our data showed curcumin concentration-dependently abrogated the proliferation of primary rat VSMCs induced by Chol...