Effects of antibiotic therapy on the early development of gut microbiota and butyrate-producers in early infants

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成果类型：

期刊论文

作者：

Qiu, Jun;Wu, Sha;Huang, Ruiwen;Liao, Zhenyu;Pan, Xiongfeng;...

通讯作者：

Xiao, ZH

作者机构：

[Qiu, Jun; Xiao, Zhenghui; Cao, Yunhui; Wu, Sha; Xiao, ZH] Univ South China, Hunan Childrens Hosp, Hengyang Med Sch, Sch Pediat,Neurol Dept, Changsha, Hunan, Peoples R China.

[Qiu, Jun; Pan, Xiongfeng; Zhao, Kunyan; Cao, Yunhui; Peng, Yunlong; Wu, Sha; Xiang, Shiting] Hunan Childrens Hosp, Pediat Res Inst Hunan Prov, Changsha, Hunan, Peoples R China.

[Liao, Zhenyu; Ma, Ye; Huang, Ruiwen] Hunan Childrens Hosp, Dept Neonatol, Changsha, Hunan, Peoples R China.

[Zhao, Kunyan] Univ South China, Sch Publ Hlth, Hengyang, Peoples R China.

[Peng, Yunlong] Soochow Univ, Dept Epidemiol & Hlth Stat, Med Coll, Suzhou, Peoples R China.

通讯机构：

[Xiao, ZH ] U

Univ South China, Hunan Childrens Hosp, Hengyang Med Sch, Sch Pediat,Neurol Dept, Changsha, Hunan, Peoples R China.

Hunan Childrens Hosp, Dept Emergency Ctr, Changsha, Peoples R China.

语种：

英文

关键词：

amoxicillin-clavulanic acid;antibiotics;butyrate-producers;gut microbiota;moxalactam

期刊：

Frontiers in Microbiology

ISSN：

1664-302X

年：

2025

卷：

页码：

1508217

DOI：

10.3389/fmicb.2024.1508217

基金类别：

Natural Science Foundation of Hunan Province, China [2023JJ30319, 2021JJ40275]; Hunan Provincial Health Commission research project [D202312057523, D20230529]; Clinical research project of Hunan Children's Hospital [2023CR01]; Clinical Research (Translation) Center of Hunan Children's Hospital, China [2023CR03]; Changsha Soft Science Research Program Project [kh2302025]

机构署名：

本校为第一且通讯机构

院系归属：

公共卫生学院

摘要：

BACKGROUND: Antibiotics, as the most commonly prescribed class of drugs in neonatal intensive care units, have an important impact on the developing neonatal gut microbiota. Therefore, comprehending the effects of commonly used antibiotic therapy on the gut microbiota and butyrate-producers in early infants could provide information for therapeutic decision-making in the NICU. OBJECTIVES: To explore the effects of antibiotic therapy on the early development of gut microbiota and butyrate-producers in early infants. METHODS: A total of 72 infant...

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Effects of antibiotic therapy on the early development of gut microbiota and butyrate-producers in early infants

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