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Co-delivery of antimicrobial peptide and Prussian blue nanoparticles by chitosan/polyvinyl alcohol hydrogels

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成果类型:
期刊论文
作者:
Liao, Zhiyi;Li, Jiayi;Ni, Wenqiang;Zhan, Rixing;Xu, Xisheng
通讯作者:
Rixing Zhan<&wdkj&>Xisheng Xu
作者机构:
[Ni, Wenqiang; Liao, Zhiyi; Li, Jiayi] Department of Burn and Plastic Surgery, the First People's Hospital of Chenzhou, University of South China, Chenzhou 423000, China
[Zhan, Rixing] Institute of Burn Research, State Key Laboratory of Trauma and Chemical Poisoning, Southwest Hospital, the Third Military Medical University, Army Medical University, Chongqing 400038, China. Electronic address: zhanrixing@tmmu.edu.cn
[Xu, Xisheng] Department of Burn and Plastic Surgery, the First People's Hospital of Chenzhou, University of South China, Chenzhou 423000, China. Electronic address: czyyxxs@126.com
通讯机构:
[Rixing Zhan] I
[Xisheng Xu] D
Department of Burn and Plastic Surgery, the First People's Hospital of Chenzhou, University of South China, Chenzhou 423000, China<&wdkj&>Institute of Burn Research, State Key Laboratory of Trauma and Chemical Poisoning, Southwest Hospital, the Third Military Medical University, Army Medical University, Chongqing 400038, China
语种:
英文
关键词:
Antibacterial;Chitosan;Metal-organic framework;Photothermal hydrogel;Prussian blue;Wound healing
期刊:
Carbohydrate Polymers
ISSN:
0144-8617
年:
2025
卷:
348
期:
Pt A
页码:
122873
基金类别:
Chongqing Youth Science and Technology Talent Training Project State Key Laboratory of Trauma Burns and Combined Injury
机构署名:
本校为第一且通讯机构
摘要:
Altered skin integrity increases the chance of infection, and bacterial infections often lead to a persistent inflammatory response that prolongs healing time. Functional artificial hydrogels are receiving increasing attention as suitable wound dressing barrier. However, the antimicrobial effect of the new dressing still needs to be explored in depth. In this work, the antimicrobial peptide MSI-1 was covalently attached to chitosan-modified poly (vinyl alcohol) hydrogels mixed with Prussian blue nanoparticles (PBNPs) via a primary amine group c...

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