期刊论文

Xu Xin Yun

英文

生物医学与环境科学：英文版

0895-3988

2020

33

8

583-592

10.3967/bes2020.077

?This project was supported by the basic research programs of Shenzhen Science and Technology Innovation Committee to XU Xin Yun 耀㨀CY? 脃嘀 Shenzhen Key ?edical ?iscipline Construction Fund 耀S?XK 脃? ?These authors contributed equally to this work ? ?Correspondence should be addressed to XU Xin Yun 唀 Tel 圀 爃爃唀 ? 爁甁ȁ崁漃圀 xyxu 鬃堁ခ紁? ?iographical notes of the first authors ? ???NG Kai ? male ? born in ? ??? ? majoring in environmental toxicology ? CAI Ying 唀 female 唀 born in 唀 ??? 唀 majoring environmental toxicology ?

本校为第一机构

Objective To screen the differentially expressed proteins (DEPs) in human bronchial epithelial cells (HBE) treated with atmospheric fine particulate matter (PM2.5). Methods HBE cells were treated with PM2.5 samples from Shenzhen and Taiyuan for 24 h. To detect overall protein expression, the Q Exactive mass spectrometer was used. Gene ontology (GO), Kyoto encyclopedia of genes and genomes (KEGG), and Perseus software were used to screen DEPs. Results Overall, 67 DEPs were screened in the Shenzhen sample-treated group, of which 46 were upregulated and 21 were downregulated. In total, 252 DEPs w...