期刊论文

Luo Xu Ling;Chen Lin Xi

英文

生物医学与环境科学：英文版

0895-3988

2019

32

5

389-392

10.3967/bes2019.053

?This study was supported by the grants from the National Natural Science Foundation of China ? ? ? ? ? ? ? ? ? ? ? Institute of ?harmacy and ?harmacology ? Learning Key Laboratory for ?harmacoproteomics ? Hunan ?rovince Cooperative Innovation Center for Molecular Target New Drug Study ? University of South China ? Hengyang ? ? ? ? ? ? ? Hunan ? China

本校为第一且通讯机构

Truttmann MC et al.[1] recently reported that AMPylation of heat shock protein 70 (HSP70) family of chaperones participates in altering the aggregation properties and maintaining protein homeostasis (proteostasis), thereby playing a vital role in the development of neurodegenerative diseases (NDs). NDs are commonly manifested by protein aggregates, which exert harmful effects on proteostasis. Interestingly, it has been observed that AMPylation of heat shock proteins (HSPs) can maintain proteostasis by inhibiting the formation of protein aggregates. As previous studies only indicate that HSPs c...

Truttmann MC et al.[1] recently reported that AMPylation of heat shock protein 70 （HSP70） family of chaperones participates in altering the aggregation properties and maintaining protein homeostasis （proteostasis）, thereby playing a vital role in the development of neurodegenerative diseases （NDs）. NDs are commonly manifested by protein aggregates, w...