期刊论文

Tang, Chao-Ke

英文

Atherosclerosis

0021-9150

2013

227

2

201-208

10.1016/j.atherosclerosis.2012.11.025

Acknowledgments The authors gratefully acknowledge the financial support from the National Natural Sciences Foundation of China (NSFC, Grant Number: 30973527, 81170278, 81070220, 81273514); Natural Sciences Foundation of Beijing (Grant Number: 7102115, NO.BZ0150); Beijing Talents Funding-Project A (Grant Number: 2011A009008000004). Authors are also grateful for grants from National S&T Major Project (Grant Number: 2012ZX09301002-004, 2012ZX09102101-020).

本校为第一且通讯机构

MicroRNAs are a group of endogenous, small non-coding RNA molecules that can induce translation repression of target genes within metazoan cells by specific base pairing with the mRNA of target genes. Recently, microRNA-33 has been discovered as a key regulator in the initiation and progression of atherosclerosis. This review highlights the impact of microRNA-33-mediated regulation in the major cardiometabolic risk factors of atherosclerosis including lipid metabolism (HDL biogenesis and cholesterol homeostasis, fatty acid, phospholipid and triglyceride, bile acids metabolism), inflammatory re...