期刊论文

Song, Guan-Bing;Zhao, Hu-Cheng

英文

Colloids and Surfaces B: Biointerfaces

0927-7765

2018

170

729-735

10.1016/j.colsurfb.2018.03.042

This work was support by grant ( CQKLBST-2017-006 from visiting scholar foundation of key laboratory of biorheological science and technology (Chongqingr), ministry of education and grant (No. 10602031 and No. 11472159 ) from National Natural Science Foundation of China.

本校为其他机构

Neuronal growth, differentiation, extension, branching and neural network activity are strongly influenced by the mechanical property of extracellular matrix (ECM). However, the mechanism by which substrate stiffness regulates a neural network activity, and the importance of ECM composition in conferring substrate stiffness sensing have not been explored. To address this question, the hippocampal neurons were seeded on the polydimethylsiloxane (PDMS) substrate with different stiffness, which were coated with fibronectin and laminin respectively...