期刊论文

中文

遗传

0253-9772

2023

45

3

221-228

10.16288/j.yczz.22-399

南华大学人才经费项目(编号:191RGC001)资助。

本校为第一机构

端粒是保护线性染色体末端的核酸-蛋白复合物。与常见的真核生物短重复序列组成的端粒不同,黑腹果蝇(Drosophila melanogaster)端粒DNA由反转座子组成,其转座行为被果蝇宿主严格限制在端粒,既实现延长端粒...展开更多 端粒是保护线性染色体末端的核酸-蛋白复合物。与常见的真核生物短重复序列组成的端粒不同,黑腹果蝇(Drosophila melanogaster)端粒DNA由反转座子组成,其转座行为被果蝇宿主严格限制在端粒,既实现延长端粒的功能,也减少转座子跳跃对基因组的损伤。但果蝇宿主是如何完成如此精确调控的机制尚不明确。目前已知的全基因组范围抑制转座子表达包括H3K9me3参与的异染色质形成途径和piRN...

Linear chromosomes of eukaryotes are protected by a DNA-protein-RNA structure called telomere.Remarkably and unlike those of most organisms studied,Drosophila telomeric DNA is not composed of a group of short repeats,but three classes of retrotransposons at the chromoso...MORE Linear chromosomes of eukaryotes are protected by a DNA-protein-RNA structure called telomere.Remarkably and unlike those of most organisms studied,Drosophila telomeric DNA is not composed of a group of short repeats,but three classes of retrotransposons at the chromosome ends.Telomeric transposons in Drosophila on the o...