版权说明 操作指南
首页 > 成果 > 详情

Serum-derived exosomes from SD rats induce inflammation in macrophages through the mTOR pathway

认领
导出
Link by DOI
反馈
分享
QQ微信 微博
成果类型:
期刊论文
作者:
Wang, Ye;Liu, Yan-ping;Sun, Zhan-bing;Deng, Wei-hua;Yuan, Xiao-yan;...
通讯作者:
Zhang, ZH
作者机构:
[Cai, Ying; Wang, Ye; Deng, Wei-hua; Yuan, Xiao-yan; Zhang, Zhao-hui; Liu, Yan-ping; Huang, Lian; Sun, Zhan-bing; Lei, Yuan-di] Univ South China, Hengyang Med Sch, Sch Publ Hlth, Dept Prevent Med, Hengyang 421001, Peoples R China.
[Zhang, Zhao-hui; Liu, Yan-ping] Univ South China, Hengyang Med Sch, Hunan Prov Key Lab Typ Environm Pollut & Hlth Haz, Hengyang, Peoples R China.
[Wang, Ye] Yingtan Maternal & Child Hlth Care Hosp, Dept Publ Hlth, Yingtan, Peoples R China.
通讯机构:
[Zhang, ZH ] U
Univ South China, Hengyang Med Sch, Sch Publ Hlth, Dept Prevent Med, Hengyang 421001, Peoples R China.
语种:
英文
关键词:
beryllium sulfate;exosomes;inflammation;lung injury;mTOR pathway
期刊:
Journal of Applied Toxicology
ISSN:
0260-437X
年:
2022
卷:
42
期:
9
页码:
1524-1532
基金类别:
Ye Wang and Yan-ping Liu contributed equally to this study. Natural Science Foundation of Hunan Province, Grant/Award Number: 2020JJ4082; National Natural Science Foundation of China, Grant/Award Number: 81573193
机构署名:
本校为第一且通讯机构
院系归属:
医学院
公共卫生学院
摘要:
Inhalation of beryllium and its compounds can cause lung injuries, resulting from inflammation and oxidative stress. Multivesicular bodies (MVB), such as exosomes, are membrane vesicles produced by early and late endosomes that mediate intercellular communications. However, the role of exosomes in beryllium toxicity has not been elucidated. This current study aimed to investigate the functional role of exosomes in lung injury resulting from beryllium sulfate (BeSO(4) ). Here, Sprague-Dawley (SD) rats were exposed to 4, 8, and 12 mg/kg BeSO(4) ...

反馈

验证码:
看不清楚,换一个
确定
取消

成果认领

标题:
用户 作者 通讯作者
请选择
请选择
确定
取消

提示

该栏目需要登录且有访问权限才可以访问

如果您有访问权限,请直接 登录访问

如果您没有访问权限,请联系管理员申请开通

管理员联系邮箱:yun@hnwdkj.com