Therapeutic potential of targeting HSPA5 through dual regulation of two candidate prognostic biomarkers ANXA1 and PSAT1 in osteosarcoma

首页 > 成果 > 详情

认领

导出

Link by DOI

反馈

作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Tang, Xiaojun;Luo, Lingli;Li, Yukun;Wu, Hailong;Hu, Qing;...

通讯作者：

Min, Shaoxiong;Zou, Juan

作者机构：

[Tang, Xiaojun; Min, Shaoxiong] Southern Med Univ, Zhujiang Hosp, Orthopaed Med Ctr, Dept Spinal Surg, Guangzhou 510280, Guangdong, Peoples R China.

[Tang, Xiaojun] Univ South China, Affiliated Hosp 2, Dept Spinal Surg, Hengyang 421001, Hunan, Peoples R China.

[Luo, Lingli] Hunan Polytech Environm & Biol, Coll Med, Hengyang 421005, Hunan, Peoples R China.

[Li, Yukun; Zou, Juan] Univ South China, Canc Res Inst, Hunan Prov Key Lab Tumor Cellular & Mol Pathol, Hengyang 421001, Hunan, Peoples R China.

[Wu, Hailong; Min, Shaoxiong] Peking Univ, Shenzhen Hosp, Dept Spinal Surg, Shenzhen 518036, Guangdong, Peoples R China.

通讯机构：

[Min, Shaoxiong] S

[Zou, Juan] U

[Min, Shaoxiong] P

Southern Med Univ, Zhujiang Hosp, Orthopaed Med Ctr, Dept Spinal Surg, Guangzhou 510280, Guangdong, Peoples R China.

Univ South China, Canc Res Inst, Hunan Prov Key Lab Tumor Cellular & Mol Pathol, Hengyang 421001, Hunan, Peoples R China.

语种：

英文

关键词：

ANXA1;HSPA5;osteosarcoma;prognosis;PSAT1

期刊：

AGING-US

ISSN：

1945-4589

年：

2021

卷：

期：

页码：

1212-1235

DOI：

10.18632/aging.202258

基金类别：

FUNDING This study was supported by the Natural Science Foundation of Guangdong Province, China (2017A030313564) and Shenzhen High-level Hospital Construction Fund to SXM and the First Affiliated Hospital of University of South China, Scientific Research Project of Hunan Department of Education (18B258) to JZ.

机构署名：

本校为通讯机构

院系归属：

医学院

摘要：

Osteosarcoma is the most common primary malignant bone tumor that mostly affects young people’s health. The prognosis of patients with unresectable or recurrent osteosarcoma still remains dismal. Based on gene integration analysis from GEO and TARGET databases by R language, the differentially expressed genes of osteosarcoma patients were identified. Biological molecular function analysis indicated that these genes were importantly enriched in the process of cell adhesion molecule binding. Gene significance highly-related to clinical traits of...

反馈

产权有误：本人成果被他人认领

数据有误：数据基本信息有误

归属有误：成果的院系归属、机构署名归属有误

其他原因：

验证码：

看不清楚，换一个

确定

取消

成果认领

标题：

用户	作者	通讯作者	--
	请选择	请选择	--

确定

取消

Therapeutic potential of targeting HSPA5 through dual regulation of two candidate prognostic biomarkers ANXA1 and PSAT1 in osteosarcoma

反馈

成果认领

提示

该栏目需要登录且有访问权限才可以访问