Project supported by Scientific Research Foundation of Hunan Province Education Department (No 02C394, 03C415, and 04B057).
机构署名:
本校为第一且通讯机构
院系归属:
医学院
摘要:
Aim: To examine the differentiation induction and growth inhibition of HL-60 cells by diallyl disulfide (DADS), and its relationship with the alterations of histone acetylation and p21WAF1 expression in vitro and in vivo. Methods: Differentiation was studied by nitroblue tetrazolium (NBT) reduction of HL-60 cell in vitro. HL-60 cells 5×106 were injected into the right side of the peritoneal cavity of severe combined immunodeficiency (SCID) mice. When the peritoneal neoplasms were detected, the SCID mice were randomly divided into 3 groups and ...
摘要(中文):
Aim:To examine the differentiation induction and growth inhibition of HL-60 cellsby diallyl disulfide(DADS),and its relationship with the alterations of histoneacetylation and p21WAF1expression in vitro and in vivo.Methods:Differentiationwas studied by nitroblue tetrazolium(NBT)reduction of HL-60 cell in vitro.HL-60cells 5×106 were injected into the right side of the peritoneal cavity of severecombined immunodeficiency(SCID)mice.When the peritoneal neoplasms weredetected,the SCID mice were randomly divided into 3 groups and received an ...