期刊论文

Liao, DF

英文

中国药理学报

1671-4083

2006

27

2

151-157

10.1111/j.1745-7254.2006.00261.x

Project supported by the National Natural Science Foundation of China （No 30171084, 30470719）, the National Major Basic Research Program of Ministry of Science and Technology of China （973）（G2000056905） and the Natural Science Foundation of Hunan （01JJY2145）.

本校为第一且通讯机构

Aim: To investigate the protective effect of high density lipoprotein 3 (HDL3) on oxidized low density lipoprotein (ox-LDL)-induced apoptosis in RAW264.7 cells. Methods: RAW264.7 cells were exposed to 50 mg/L ox-LDL for various durations up to 48 h, and apoptosis was detected using Hoechst 33258 staining and flow cytometric analysis. Total cholesterol levels were detected by high performance liquid chromatography, cholesterol efflux was determined by Tritium labeling, and the cellular lipid droplets were assayed by oil red O staining. Results: ...

Aim:To investigate the protective effect of high density lipoprotein 3（HDL3）onoxidized low density lipoprotein（ox-LDL）-induced apoptosis in RAW264.7 cells,Methods:RAW264.7 cells were exposed to 50 mg/L ox-LDL for various durationsup to 48h,and apoptosis was detected using Hoechst 33258 staining and flowcytometric analysis.Total cholesterol levels were detected by high performanceliquid chromatography,cholesterol efflux was determined by Tritium labeling,andthe cellular lipid droplets were assayed by oil red O staining.Results:Treatmentwith...