Background::
Icariin (ICA), one of the main effective components isolated from the traditional
Chinese herb Epimedium brevicornu Maxim., has been reported to possess extensive pharmacological
actions, including enhanced sexual function, immune regulation, anti-inflammation, and antiosteoporosis.
Methods::
Our study was designed to investigate the effect of ICA on cell proliferation and differentiation
and the molecular mechanism of OPG/RANKL mediated by the Estrogen Receptor (ER) in
hFOB1.19 human osteoblast cells.
Results::
The experimental results show that ICA can stimulate cell prolif...
