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MicroRNAs: Key regulators of endothelial progenitor cell functions

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成果类型:
期刊论文
作者:
Qu, Kai;Wang, Zuo*;Lin, Xiao-long;Zhang, Kai;He, Xing-lan;...
通讯作者:
Wang, Zuo
作者机构:
[Qu, Kai; Wang, Zuo; He, Xing-lan; Zhang, Hai] Univ South China, Key Lab Atherosclerol Hunan Prov, Inst Cardiovasc Res, Hengyang 421001, Hunan, Peoples R China.
[Lin, Xiao-long] Third Peoples Hosp Huizhou, Dept Pathol, Huizhou 516002, Guangdong, Peoples R China.
[Zhang, Kai] Univ South China, Hosp 2, Hengyang 421001, Hunan, Peoples R China.
通讯机构:
[Wang, Zuo] U
Univ South China, Key Lab Atherosclerol Hunan Prov, Inst Cardiovasc Res, Hengyang 421001, Hunan, Peoples R China.
语种:
英文
关键词:
Angiogenesis;Cardiovascular diseases;Endothelial progenitor cells;MicroRNA
期刊:
Clinica Chimica Acta
ISSN:
0009-8981
年:
2015
卷:
448
页码:
65-73
机构署名:
本校为第一且通讯机构
院系归属:
医学院
药学与生物科学学院
摘要:
Development of cardiovascular diseases mobilises endothelial progenitor cells (EPCs) from the bone marrow to participate in vascular repair and formation of new blood vessels under both pathological and physiological conditions. Therefore, EPCs show great potential for therapeutic applications; however, the phenotypic and functional characterisation of EPCs is still difficult because controversies exist regarding their accurate definition. Growing studies have shown modest clinical benefits of EPCs; however, it is necessary to better understand...

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