Analysis of microRNA expression profiles in human bronchial epithelial cells infected by Chlamydia psittaci

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成果类型：

期刊论文

作者：

Liu, Luyao;Chen, Xi;Tang, Ting;Chen, Li;Huang, Qiaoling;...

通讯作者：

Chen, Lili

作者机构：

[Chen, Xi; Tang, Ting; Bai, Qinqin; Liu, Luyao; Chen, Lili; Huang, Qiaoling; Chen, Li] Univ South China, Coll Publ Hlth, Dept Publ Hlth Lab Sci, Hengyang, Peoples R China.

[Chen, Xi; Tang, Ting; Liu, Luyao; Chen, Lili; Huang, Qiaoling; Chen, Li] Key Lab Hengyang Hlth Hazard Factors Inspect & Qu, Hengyang, Peoples R China.

[Tang, Ting] First Peoples Hosp Yunnan Prov, Dept Infect Control, Kunming, Yunnan, Peoples R China.

[Li, Zhongyu] Univ South China, Hengyang Med Coll, Inst Pathogen Biol, Hengyang, Peoples R China.

通讯机构：

[Lili Chen] D

Department of public health laboratory sciences, College of Public Health, University of South China, Hengyang, China<&wdkj&>Key Laboratory of Hengyang for Health Hazard Factors Inspection and Quarantine, Hengyang, China

语种：

英文

关键词：

Chlamydia psittaci;Gene expression profile;Gene regulation;Small RNA-Seq;microRNA

期刊：

Microbial Pathogenesis

ISSN：

0882-4010

年：

2021

卷：

154

页码：

104837

DOI：

10.1016/j.micpath.2021.104837

基金类别：

Natural Science Foundation of Hunan ProvinceNatural Science Foundation of Hunan Province [2020JJ4527, 2019JJ50494]; Scientific Research Fund of Hunan Provincial Education DepartmentHunan Provincial Education Department [20A438]; Fund of Hunan Key Laboratory [2019TP1027]; Fund of Hengyang Engineering Center [2020KJ67]

机构署名：

本校为第一机构

院系归属：

医学院

公共卫生学院

摘要：

Background: Chlamydia psittaci is a pathogen of birds that can cause zoonotic disease in mammals including pneumonia in humans. MicroRNAs (miRNAs) are a class of small non-coding RNA fragments with a length of about 22 nt, which play an important role in regulating gene expression after transcription. Chlamydia infection can cause changes in host cell miRNA expression, but the potential biological function of miRNAs in C. psittaci infection and pathogenesis is not well understood. Methods: Small RNA sequencing (sRNA-Seq) technology was used to characterise miRNA expression in human bronchial e...

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Analysis of microRNA expression profiles in human bronchial epithelial cells infected by Chlamydia psittaci

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