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The role of CoQ10 in embryonic development

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成果类型:
期刊论文
作者:
He, Xueke;Chen, Hao;Liao, Minjun;Zhao, Xiaomei;Zhang, Dawei;...
通讯作者:
Jiang, M
作者机构:
[He, Xueke; Jiang, Miao; Liao, Minjun; Jiang, M; Chen, Hao] Univ South China, Hunan Int Sci & Technol Cooperat Base Arterioscle, Key Lab Arteriosclerol Hunan Prov, Inst Cardiovasc Dis,Hengyang Med Sch, Hengyang 421001, Hunan, Peoples R China.
[Zhao, Xiaomei] Univ South China, Coll Publ Hlth, Hengyang 421001, Hunan, Peoples R China.
[Zhang, Dawei] Univ Alberta, Fac Med & Dent, Dept Pediat, Grp Mol & Cell Biol Lipids, Edmonton, AB, Canada.
[Jiang, Zhisheng] Univ South China, Inst Cardiovasc Dis, Dept Pathophysiol,Postdoctoral Res Stn Basic Med, Key Lab Arteriosclerol Hunan Prov,Hunan Int Sci &, Hengyang 421001, Peoples R China.
通讯机构:
[Jiang, M ] U
Univ South China, Hunan Int Sci & Technol Cooperat Base Arterioscle, Key Lab Arteriosclerol Hunan Prov, Inst Cardiovasc Dis,Hengyang Med Sch, Hengyang 421001, Hunan, Peoples R China.
语种:
英文
关键词:
CoQ10;Embryonic development;Germ cells;Mitochondrial electron transport chain (mETC)
期刊:
Journal of Assisted Reproduction and Genetics
ISSN:
1058-0468
年:
2024
基金类别:
Natural Science Foundation of Hunan Province
机构署名:
本校为第一且通讯机构
院系归属:
医学院
公共卫生学院
摘要:
Coenzyme Q10 (CoQ10) is a natural component widely present in the inner membrane of mitochondria. CoQ10 functions as a key cofactor for adenosine triphosphate (ATP) production and exhibits antioxidant properties in vivo. Mitochondria, as the energy supply center of cells, play a crucial role in germ cell maturation and embryonic development, a complicated process of cell division and cellular differentiation that transforms from a single cell (zygote) to a multicellular organism (fetus). Here, we discuss the effects of CoQ10 on oocyte maturation and the important role of CoQ10 in the growth of...

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