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Facile synthesis and self-assembly behaviors of biodegradable amphiphilic hyperbranched copolymers with reducible poly(caprolactone) grafts

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成果类型:
期刊论文
作者:
Zhang, Xianshuo;Wang, Peipei;Xu, Yaoyu;Wang, Jun;Shi, Yunfeng;...
通讯作者:
Shi, Yunfeng(shiyunfeng2009@gmail.com);Wei, Hua(weih@usc.edu.cn)
作者机构:
[Xu, Yaoyu; Zhang, Xianshuo; Liu, Ruru; Wang, Peipei; Shi, Yunfeng; Song, Wenjing; Niu, Wenxu] Anyang Normal Univ, Sch Chem & Chem Engn, Anyang 455000, Henan, Peoples R China.
[Wei, Hua; Wang, Jun; Yu, Cui-Yun] Univ South China, Hunan Prov Cooperat Innovat Ctr Mol Target New Dr, Dept Pharm & Pharmacol, Hengyang 421001, Peoples R China.
通讯机构:
[Yunfeng Shi] S
[Hua Wei] H
School of Chemistry and Chemical Engineering, Anyang Normal University, Anyang, Henan 455000, China<&wdkj&>Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, Department of Pharmacy and Pharmacology, University of South China, Hengyang, China
语种:
英文
期刊:
Polymer Chemistry
ISSN:
1759-9954
年:
2022
卷:
13
期:
43
页码:
6162-6170
基金类别:
National Natural Science Foundation of China [51473072, 21504035]; Key Research and Development and Promotion Projects of Henan Province [222102230115]; Key Research Projects, Universities of Henan Province [21A150007]; Key Research and Development and Promotion Projects of Anyang City [2022C01SF082]; research cultivating fund of Anyang Normal University [AYNUKPY-2020-13]
机构署名:
本校为其他机构
院系归属:
药学与生物科学学院
摘要:
The facile synthesis of amphiphilic hyperbranched copolymers with biodegradability generally suffers from sophisticated specific design and multistep preparation procedures integrating different synthetic approaches, leading to difficulty and complexity in scalable manufacture and potential biomedical applications. To develop a robust yet facile strategy toward biodegradable hyperbranched amphiphilic copolymers, we reported in this study the design and synthesis of a reducible macromonomer, 2-((2-hydroxyethyl)disulfanyl)ethyl methacrylate-graft...

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