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Investigation for Regulation of a DNA-Programmed Bimetallic Nanozyme and Its Biosensing Applications

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成果类型:
期刊论文
作者:
Xiao, Jiaxuan;Yang, Xiaofeng;Zhang, Xinshuo;Niu, Xiangheng;Guo, Yujia;...
通讯作者:
Zhang, Z
作者机构:
[Guo, Yujia; Xiao, Jiaxuan; Yang, Xiaofeng; Zhu, Nuanfei; Zhang, Zhen; Zhang, Z; Zhang, Xinshuo; Zeng, Kun] Jiangsu Univ, Sch Environm & Safety Engn, Zhenjiang 212013, Peoples R China.
[Niu, Xiangheng] Univ South China, Sch Publ Hlth, Hengyang Med Sch, Hengyang 421001, Peoples R China.
通讯机构:
[Zhang, Z ] J
Jiangsu Univ, Sch Environm & Safety Engn, Zhenjiang 212013, Peoples R China.
语种:
英文
期刊:
Analytical Chemistry
ISSN:
0003-2700
年:
2024
卷:
96
期:
49
页码:
19796-19802
基金类别:
National Natural Science Foundation of China [22176075, 22476072]; National Natural Science Foundation of China [SJCX20_1408]; Graduate Research and Innovation Projects of Jiangsu Province; Jiangsu Collaborative Innovation Center of Technology and Material of Water Treatment
机构署名:
本校为其他机构
院系归属:
公共卫生学院
摘要:
The DNA-mediated growth strategy of bimetallic nanozymes is considered as an effective approach to regulate their peroxidase activity via tuning the morphology and nanostructure. Albeit important, its biosensing application in rational methods' design and performance improvement is limited due to the deficiency of a systematic understanding of the interactions between DNA and nanomaterials used. Herein, four homo-oligonucleotides as capping ligands were employed to functionalize the bimetallic nanozymes, where Pt nanoparticles (PtNPs) were in s...

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