版权说明 操作指南
首页 > 成果 > 详情

A Smartphone-Mediated "All-In-One" Biosensing Chip for Visual and Value-Assisted Detection

认领
导出
Link by DOI
反馈
分享
QQ微信 微博
成果类型:
期刊论文
作者:
Xu, Jing;Li, Yujin;Wang, Futing;Yang, Hongfen;Huang, Ke-Jing;...
通讯作者:
Cai, R;Yang, HF
作者机构:
[Xu, Jing; Li, Yujin] Xinyang Normal Univ, Coll Chem & Chem Engn, Xinyang 464000, Peoples R China.
[Li, Yujin; Wang, Futing; Cai, Ren; Tan, Weihong] Hunan Univ, Coll Mat Sci & Engn, Coll Chem & Chem Engn, Coll Biol,Mol Sci & Biomed Lab,State Key Lab Chemo, Changsha 410082, Hunan, Peoples R China.
[Huang, Ke-Jing] Guangxi Minzu Univ, Sch Chem & Chem Engn, Nanning 530006, Peoples R China.
[Tan, Weihong] Chinese Acad Sci, Univ Chinese Acad Sci, Zhejiang Canc Hosp, Canc Hosp, Hangzhou 310022, Zhejiang, Peoples R China.
[Tan, Weihong] Shanghai Jiao Tong Univ, Inst Mol Med, Sch Med, Renji Hosp, Shanghai 200240, Peoples R China.
通讯机构:
[Yang, HF ] U
[Cai, R ] H
Hunan Univ, Coll Mat Sci & Engn, Coll Chem & Chem Engn, Coll Biol,Mol Sci & Biomed Lab,State Key Lab Chemo, Changsha 410082, Hunan, Peoples R China.
Univ South China, Sch Publ Hlth, Hengyang Med Sch, Hunan Key Lab Typ Environm Pollut & Hlth Hazards, Hengyang 421001, Peoples R China.
语种:
英文
期刊:
Analytical Chemistry
ISSN:
0003-2700
年:
2024
卷:
96
期:
39
页码:
15780-15788
基金类别:
Natural Science Foundation of China [22004032, 22074130]; Key Scientific Research Projects of Henan Province [232102320040]; Program for Innovative Research Team (in Science and Technology) in University of Henan Province [24IRTSTHN004]; Henan Educational Committee [24B150034]; Hunan Provincial Natural Science Foundation of China [2024JJ5348, 2021JJ20020]; Nanhu Scholars Program for Young Scholars of XYNU; Analysis Testing Center of Xinyang Normal University
机构署名:
本校为通讯机构
院系归属:
公共卫生学院
摘要:
A smartphone-mediated self-powered biosensor is fabricated for miRNA-141 detection based on the CRISPR/Cas12a cross-cutting technique and a highly efficient nanozyme. As a novel nanozyme and a signal-amplified coreaction accelerator, the AuPtPd@GDY nanozyme exhibits an excellent ability to catalyze cascade color reactions and high conductivity to enhance the electrochemical signal for miRNA-141 assays. After CRISPR/Cas12a cross-cutting of S2-glucose oxidase (S2-GOD), the electrochemical signal is weakened, and miRNA-141 is detected by monitoring the decrease in the signal. On the other hand, a...

反馈

验证码:
看不清楚,换一个
确定
取消

成果认领

标题:
用户 作者 通讯作者
请选择
请选择
确定
取消

提示

该栏目需要登录且有访问权限才可以访问

如果您有访问权限,请直接 登录访问

如果您没有访问权限,请联系管理员申请开通

管理员联系邮箱:yun@hnwdkj.com