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Impact of MiRNAs and LncRNAs on Multidrug Resistance of Gastric Cancer

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成果类型:
期刊论文
作者:
Wu, Yiwen;Yang, Xiaoyan;Xie, Zhizhong;Hu, Haihong;Lei, Xiaoyong;...
通讯作者:
Yang, X.
作者机构:
[Yang, Xiaoyan; Xie, Zhizhong; Niu, Dun; Hu, Haihong; Li, Shiyan; Lei, Xiaoyong; Tuo, Lu; Wu, Yiwen] Univ South China, Inst Pharm & Pharmacol, Hengyang Med Sch, Sch Pharm, 28 Western Changsheng Rd, Hengyang 421001, Hunan, Peoples R China.
[Yang, Xiaoyan; Xie, Zhizhong; Lei, Xiaoyong] Univ South China, Hunan Prov Key Lab Tumor Microenvironm Respons Dr, Hengyang 421001, Hunan, Peoples R China.
通讯机构:
[Yang, X.] I
Institute of Pharmacy and Pharmacology, 28 Western Changsheng Road, Hunan, China
语种:
英文
关键词:
gastric cancer;LncRNAs;MiRNAs;Multidrug;ncRNAs;resistance
期刊:
COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING
ISSN:
1386-2073
年:
2022
卷:
25
期:
13
页码:
2127-2140
基金类别:
This work was funded by the Hengyang City Science and Technology Planning Project [grant number 202150063473], the Scientific Research Project of Hunan Provincial Health Commission [grant number 202202044140], the Scientific Research Project of Hunan Provincial Education Department [grant number 21B0438], the Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study [grant number 2014-405], and Undergraduate Training Program for Innovation and Entrepreneurship of Hunan Prov-inceg[rant number2x02110555455].
机构署名:
本校为第一机构
院系归属:
药学与生物科学学院
摘要:
Multi-drug resistance (MDR) is characterized by the resistance of tumor cells to some antitumor drugs with different structures and mechanisms after the use of a single chemotherapy drug or even the first use of the drug. Notably, MDR has become the largest obstacle to the success of gastric cancer chemotherapies. Non-coding RNAs are defined as a class of RNAs that do not have the ability to code proteins. They are widely involved in important biological functions in life activities. Multiple lines of evidence demonstrated that ncRNAs are closely related to human cancers, including gastric can...

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