Synthesis of Acetamides from Aryl Amines and Acetonitrile by Diazotization under Metal-Free Conditions

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成果类型：

期刊论文

作者：

Zeng, Yao-Fu;Li, Yi-Na;Zhang, Na-Na;Kang, Huan;Duan, Pan;...

通讯作者：

Wen, Xianghao

作者机构：

[Guo, Yu; Zeng, Yao-Fu; Xiao, Fang; Li, Yi-Na] Univ South China, Inst Pharm & Pharmacol, Hengyang 421001, Peoples R China.

[Kang, Huan; Guo, Yu; Zeng, Yao-Fu; Zhang, Na-Na; Duan, Pan] Univ South China, Sch Pharmaceut Sci, Hengyang 421001, Peoples R China.

[Wen, Xianghao] Univ South China, Affiliated Nanhua Hosp, Hengyang 421001, Peoples R China.

通讯机构：

[Wen, Xianghao] U

Univ South China, Affiliated Nanhua Hosp, Hengyang 421001, Peoples R China.

语种：

英文

关键词：

aryl amines;amidation;acetonitrile;diazotization;acetamides;coupling reaction

期刊：

SYNLETT

ISSN：

0936-5214

年：

2019

卷：

期：

页码：

2169-2172

DOI：

10.1055/s-0039-1690237

基金类别：

This research was supported by the "Double First-Class" Discipline Construction Foundation of the University of South China (2017SYL06), the Undergraduate Training Programs for Innovation and Entrepreneurship in Hunan Province (S201910555144), and the Foundation of Hunan Educational Committee (18C0476, 18C0467).

机构署名：

本校为第一且通讯机构

院系归属：

药学与生物科学学院

摘要：

An efficient and metal-free coupling reaction has been developed that affords acetamides from the corresponding aryl amines and acetonitrile. This method tolerates a wide range of functional groups and is selective toward aryl amines. Preliminary mecha...

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Synthesis of Acetamides from Aryl Amines and Acetonitrile by Diazotization under Metal-Free Conditions

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