Fibrosis, the self-repair process of the body after tissue damage, is a common pathological feature of many chronic inflammatory diseases. It occurs in a variety of organs, leading to structural destruction and hypofunction, and even organ failure. Fibrosis in organ tissues is characterized by chronic inflammation, excessive accumulation of extracellular matrix (ECM) components, and the decrease of parenchymal cells. Fibrosis is caused by persistent infections, toxins, autoimmune diseases, radiation, and mechanical injury. To date, there are various therapeutic strategies for organ fibrosis, s...
