Iron regulatory protein 2 (IRP2), first separated from mouse in 1993,is a cytoplasmic iron-regulated RNA-binding protein. IRP2 is a subtype of iron regulatory proteins (IRPs). IRP2 binds to ironresponsive element (IRE) RNA sequence to maintain iron homeostasis [1]. IRP2 can easily be hydrolyzed by protease because of its unique sequence of 73 amino acids. In general, IRP2 is widely expressed in many tissues, including fat, lung, brain, stomach, liver, heart, th...
