Pancreatitis, the pancreas digestion itself as well as its surroundings, is a potentially fatal disease involved in severe public health care burdens [1]. It is broadly classified into acute and chronic pancreatitis. The incidence of acute pancreatitis is 13–45 cases per 100,000 persons each year worldwide. Compared with acute pancreatitis, chronic pancreatitis, although lower in prevalence than acute pancreatitis, has profound effects on the patient’s quality of life. It has long been recognized that the pancreas is prominently sensitive to ...