期刊论文

Tian, Ying

英文

生物化学与生物物理学报

1672-9145

2015

47

11

915-924

10.1093/abbs/gmv098

This work was supported by the grants from the National Natural Science Foundation of China （No. 81371485）, the Zhengxiang Scholar Program of University of South China （2014-004）, and the Construct Program of the Key Discipline in Hunan Province.

本校为第一且通讯机构

Corticosterone, one of the glucocorticoids, is toxic to neurons and plays an important role in depressive-like behavior and depression. We previously showed that hydrogen sulfide (H2S), a novel physiological mediator, plays an inhibitory role in depression. However, the mechanism underlying H2S-triggered antidepressant-like role is not clearly known. Brain-derived neurotrophic factor (BDNF), a neurotrophic factor, plays a neuroprotective role that is mediated by its high-affinity tropomysin-related kinase B (TrkB) receptor. In this study, to investigate the underlying mechanism of H2S-induced ...