Background Neuropathic pain (NP), characterized by variable symptoms, treatment resistance, and substantial physical/psychological burdens, impacts 40%-60% of spinal cord injury (SCI) patients. Due to the unpredictable onset and pervasive nature of NP, timely intervention cannot be made, so self-management strategies become necessary. However, limitations are present in these strategies. Therefore, we conducted a meta-synthesis of qualitative studies to explore how the complexity of NP (physical, emotional, and social challenges) interferes with self-management effectiveness, thereby guiding t...