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Use of recombinant Lactobacillus sakei for the prevention and treatment of radiation-induced enteritis

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成果类型:
期刊论文
作者:
He, Jun-yan;Wang, Wu-zhou;Qi, Hui-zhou;Ma, Yun;He, Shu-ya*
通讯作者:
He, Shu-ya
作者机构:
[He, Shu-ya; Wang, Wu-zhou; He, Jun-yan; Ma, Yun; Qi, Hui-zhou] Univ South China, Med Coll, Hengyang, Peoples R China.
[He, Shu-ya; Wang, Wu-zhou; He, Jun-yan; Ma, Yun] Univ South China, Dept Biochem & Mol Biol, Hengyang 421001, Peoples R China.
通讯机构:
[He, Shu-ya] U
Univ South China, Dept Biochem & Mol Biol, Hengyang 421001, Peoples R China.
语种:
英文
期刊:
Medical Hypotheses
ISSN:
0306-9877
年:
2018
卷:
119
页码:
37-40
基金类别:
National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81741143]; Education Department of Hunan Province, China [17A186]; Natural Science Foundation of Hunan Province, ChinaNatural Science Foundation of Hunan Province [2018JJ3458]
机构署名:
本校为第一且通讯机构
院系归属:
化学化工学院
医学院
药学与生物科学学院
摘要:
Radiation-induced enteritis is one of the most common complications in patients under radiotherapy at abdominal or pelvic cavity. Up to 50% of patients treated with pelvic radiotherapy has been reported radiation-induced acute enteritis, and half of them developed chronic enteritis. Overproduction of free radicals, activation of inflammatory pathways and vascular endothelial dysfunction were considered as the primary mechanisms of radiation-induced enteritis. Because probiotics have been demonstrated as a promising potential candidate for treating intestinal diseases, it may be a safer and mor...

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