Optimization of sub-arc collimator angles in volumetric modulated arc therapy: a heatmap-based blocking index approach for multiple brain metastases

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成果类型：

期刊论文

作者：

Huang, Shi-Xiong;Yang, Song-Hua;Zeng, Biao;Li, Xiao-Hua

通讯作者：

Li, XH;Zeng, B

作者机构：

[Li, Xiao-Hua; Huang, Shi-Xiong; Li, XH] Univ South China, Sch Nucl Sci & Technol, Hengyang 421001, Peoples R China.

[Zeng, Biao; Zeng, B; Huang, Shi-Xiong] Cent South Univ, Hunan Canc Hosp, Affiliated Canc Hosp, Dept Radiat Oncol,Xiangya Sch Med, Changsha 410013, Hunan, Peoples R China.

[Yang, Song-Hua] Cent South Univ, Hunan Canc Hosp, Dept Clin Pharmaceut Res Inst, Affiliated Canc Hosp,Xiangya Sch Med, Changsha 410013, Hunan, Peoples R China.

通讯机构：

[Zeng, B ] C

[Li, XH ] U

Univ South China, Sch Nucl Sci & Technol, Hengyang 421001, Peoples R China.

Cent South Univ, Hunan Canc Hosp, Affiliated Canc Hosp, Dept Radiat Oncol,Xiangya Sch Med, Changsha 410013, Hunan, Peoples R China.

语种：

英文

关键词：

Multiple brain metastases;VMAT;Sub-arc;Collimator angle optimization

期刊：

Physical and Engineering Sciences in Medicine

ISSN：

2662-4729

年：

2024

页码：

1-12

DOI：

10.1007/s13246-024-01477-y

基金类别：

The study was supported by the following projects: The study was supported by the following projects: Hunan Cancer Hospital Climb Plan QH2023001; Hunan Provincial Natural Science Foundation of China 2023JJ60322; Scientific Research Project of Hunan Provincial Health Commission 202319015975; Hunan Cancer Hospital Climb Plan KY2021141.

机构署名：

本校为第一且通讯机构

院系归属：

核科学技术学院

摘要：

To develop and assess an automated Sub-arc Collimator Angle Optimization (SACAO) algorithm and Cumulative Blocking Index Ratio (CBIR) metrics for single-isocenter coplanar volumetric modulated arc therapy (VMAT) to treat multiple brain metastases. This study included 31 patients with multiple brain metastases, each having 2 to 8 targets. Initially, for each control point, the MLC blocking index was calculated at different collimator angles, resulting in a two-dimensional heatmap. Optimal sub-arc segmentation and collimator angle optimization we...

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Optimization of sub-arc collimator angles in volumetric modulated arc therapy: a heatmap-based blocking index approach for multiple brain metastases

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