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The GCAG Haplotype of the CRHBP Gene May Decrease the Risk for Robbery Behavior among the Han Chinese

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成果类型:
期刊论文
作者:
Tang, Liang;Chen, Yongjun;Xiang, Qin;Xiang, Ju;Tang, Yonghong*;...
通讯作者:
Li, Jianming;Tang, Yonghong
作者机构:
[Li, Jianming; Xiang, Qin; Xiang, Ju; Tang, Liang] Xiangya Boai Rehabil Hosp, Dept Rehabil, 61 North Wanjiali Rd,Xianglong St, Changsha 410100, Peoples R China.
[Li, Jianming; Xiang, Qin; Xiang, Ju; Tang, Liang] Changsha Med Univ, Dept Anat, Changsha, Peoples R China.
[Tang, YH; Li, JM; Li, Jianming; Tang, Yonghong; Chen, Yongjun] Univ South China, Nanhua Affiliated Hosp, Dept Neurol, Dongfeng Rd, Hengyang 421001, Peoples R China.
通讯机构:
[Li, Jianming] X
[Tang, YH; Li, JM] U
Xiangya Boai Rehabil Hosp, Dept Rehabil, 61 North Wanjiali Rd,Xianglong St, Changsha 410100, Peoples R China.
Univ South China, Nanhua Affiliated Hosp, Dept Neurol, Dongfeng Rd, Hengyang 421001, Peoples R China.
语种:
英文
关键词:
CRHBP;Chinese population;haplotype;polymorphism;robbery behavior
期刊:
GENETIC TESTING AND MOLECULAR BIOMARKERS
ISSN:
1945-0265
年:
2020
卷:
24
期:
7
页码:
436-442
基金类别:
This study was funded by the National Natural Science Foundation of China (Grant Nos. 81873780 and 61702054); Hunan Natural Science Foundation Youth Program (2019JJ50697); The Changsha Outstanding Innovative Young People Training Scheme (kq1905047, kq1905045); The Foundation of the Education Department of Hunan Province (16A027, 19A058); The Foundation of Health and Family Planning Commission of Hunan Province (20201918); The Application Characteristic Discipline of Hunan Province; The Hunan Key Laboratory Cultivation Base of the Research and Development of Novel Pharmaceutical Preparations (No. 2016TP1029); The Clinical Research Center of Neurodegenerative Diseases in Hunan province (2018SK4002); The Hunan Provincial Innovation Platform and Talents Program (No. 2018RS3105); The Hunan Provincial Science and Technology Department and Hunan Provincial Health and Family Planning Commission (Grant No. [2018]85); The Natural Science Foundation of Hunan Province (Grant No. [2017]1); The Key Project of Hunan Provincial Commission of Health and Family Planning (Grant No. [2017]144); The Hunan Province Science and Technology Major Project (Grant No. [2016]158); Hunan Provincial Science and Technology Department Clinical Medical Technology Innovation Guide Project (2018SK51711).
机构署名:
本校为通讯机构
院系归属:
医学院
摘要:
Aims: Hypothalamic-pituitary-adrenocortical axis gene polymorphisms have been reported to affect aggressive behavior. Corticotropin releasing hormone binding protein (CRHBP) polymorphisms have been shown to contribute to the susceptibility to stress-related disorders, including aggressive behavior. However, no study has been conducted on the relationship between CRHBP polymorphisms and aggressive behavior risk in the Han Chinese population. Methods: A case-control study that comprised 194 male criminals and 303 healthy controls was carried out ...

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