N-aminomorpholine-functionalized bromine-doped carbon dots for hypochlorous acid detection in foods and imaging in live cells

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成果类型：

期刊论文

作者：

Zhao, Chengda;Yuan, Pengxiang;Wang, Dan;Li, Shiyao;Yao, Huan;...

通讯作者：

Wang, Li-Li;Du, FF

作者机构：

[Zhao, Chengda] Univ South China, Affiliated Nanhua Hosp, Hengyang Med Sch, Dept Anesthesiol, Hengyang 421001, Hunan, Peoples R China.

[Wang, Li-Li; Du, Fangfang] Hainan Med Univ, Affiliated Hosp 1, Key Lab Hainan Trauma & Disaster Rescue, Haikou 571199, Peoples R China.

[Du, Fangfang] Hainan Med Univ, Minist Educ, Coll Emergency & Trauma, Engn Res Ctr Hainan Biosmart Mat & Biomed Devices,, Haikou 571199, Peoples R China.

[Yang, Liu-Pan; Li, Shiyao; Wang, Dan; Wang, Li-Li; Yuan, Pengxiang; Yao, Huan] Univ South China, Sch Pharmaceut Sci, Hengyang Med Sch, Hengyang 421001, Hunan, Peoples R China.

通讯机构：

[Wang, LL; Du, FF ] H

Hainan Med Univ, Affiliated Hosp 1, Key Lab Hainan Trauma & Disaster Rescue, Haikou 571199, Peoples R China.

语种：

英文

关键词：

Bromine-doped carbon dots;Fluorescent probe;Food safety;HClO sensing;Lysosome-targetable imaging;N-aminomorpholine-functionalized

期刊：

Food Chemistry

ISSN：

0308-8146

年：

2024

卷：

441

页码：

138284

DOI：

10.1016/j.foodchem.2023.138284

基金类别：

National Natural Science Foundation of China [22174059]; Scientific Research Project of Hunan Provincial Health Commission [D202313027525]; Natural Science Foundation of Hunan Province [2022JJ40363]; Excellent Youth Funding of Hunan Provincial Education Department [22B0460]

机构署名：

本校为第一机构

院系归属：

医学院

摘要：

Hypochlorous acid (HClO) is used in food preservation. However, excessive HClO can deteriorate nutritional composition of food, compromise its quality, and potentially induce various diseases. Consequently, the development of multifunctional fluorescent probes for the sensitive and selective detection of HClO is highly anticipated for food safety. In this work, we designed a nanoprobe using N-aminomorpholine (AM)-functionalized bromine-doped carbon dots (Br-CDs-AM) for sensing HClO. This nanoprobe exhibits pH stability, strong resistance to photobleaching, superior long-term photostability (12...

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N-aminomorpholine-functionalized bromine-doped carbon dots for hypochlorous acid detection in foods and imaging in live cells

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