Chinese National Natural Science FoundationNational Natural Science Foundation of China (NSFC) [81101274, 30972576]; Hunan Provincial Natural Science-Hengyang Joint Foundation [10JJ2010]; Hunan Provincial Natural Science FoundationNatural Science Foundation of Hunan Province [2011JJ3104]
机构署名：
本校为第一且通讯机构
院系归属：
医学院
摘要：
Introduction: The aim of this study is to determine whether regulation of the expression level of fms-like tyrosine kinase-4 (Flt-4) is related to osteoclast differentiation. Material and methods: Osteoclast formation and differentiation of mouse bone marrow cells and RAW264.7 cells were performed. To induce osteoclast differentiation, RANKL (50 ng/ml) with or without vascular endothelial growth factor-C (VEGF-C) and vascular endothelial growth factor-D (VEGF-D) was added to mouse bone marrow cells and RAW264.7 cells. Then cells were examined u...
