National Natural Science Foundation of China (NSFC)National Natural Science Foundation of China (NSFC) [21032006, 21172240]; 973 Program of ChinaNational Basic Research Program of China [2012CBA01200]; Chinese Academy of SciencesChinese Academy of Sciences
机构署名：
本校为其他机构
院系归属：
药学与生物科学学院
摘要：
The decarboxylation of potassium 2-pyridinyl sulfonyldifluoroacetate and its subsequent reaction with aldehydes was found to be an efficient approach for the Julia-Kocienski reaction under mild conditions to give gem-difluoro olefins in moderate to excellent yields. Owing to its high stability in the pure state and its easy decarboxylation in polar solvents, potassium 2-pyridinyl sulfonyldifluoroacetate is expected to be an efficient gem-difluoro-olefination reagent. The decarboxylation of potassium 2-pyridinyl sulfonyldifluoroacetate and its s...
