期刊论文

Yi, Guang-Hui

英文

Advanced Drug Delivery Reviews

0169-409X

2016

106

10

132-147

10.1016/j.addr.2016.04.030

This study was supported by grants from the National Natural Science Foundation of China (NO. 81270360 and 81100211 ), the Science and Technology Plan Key Projects of Hunan Province (NO. 2014FJ2012 ), the Natural Sciences Foundation of Hunan Province (NO. 2016JJ6133 ), the Aid Program for Science and Technology Innovative Research Team in Higher Educational Institutions ( 2008-244 ) of Hunan Province, the Construct Program of the Key Discipline in Hunan Province (Basic Medicine Sciences in University of South China), and the Zhengxiang Scholar Program of the University of South China (Xiangyang Tang).

本校为第一且通讯机构

High-density lipoprotein (HDL) is a comparatively dense and small lipoprotein that can carry lipids as a multifunctional aggregate in plasma. Several studies have shown that increasing the levels or improving the functionality of HDL is a promising target for treating a wide variety of diseases. Among lipoproteins, HDL particles possess unique physicochemical properties, including naturally synthesized physiological components, amphipathic apolipoproteins, lipid-loading and hydrophobic agent-incorporating characteristics, specific protein–prot...