High-density lipoprotein subclass and particle size in coronary heart disease patients with or without diabetes

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成果类型：

期刊论文

作者：

Tian, Li;Long, Shiyin;Li, Chuanwei;Liu, Yinghui;Chen, Yucheng;...

通讯作者：

Fu, Mingde

作者机构：

[Tian, Li; Long, Shiyin; Liu, Yinghui; Fu, Mingde] Sichuan Univ, W China Hosp, Lab Endocrinol & Metab, Chengdu 610041, Sichuan, Peoples R China.

[Tian, Li; Liu, Yinghui; Fu, Mingde] Sichuan Univ, State Key Lab Biotherapy, Chengdu 610041, Sichuan, Peoples R China.

[Long, Shiyin] Univ S China, Dept Biochem & Mol Biol, Hengyang, Hunan, Peoples R China.

[Zeng, Zhi; Chen, Yucheng; Li, Chuanwei] Sichuan Univ, W China Hosp, Cardiovasc Dept, Chengdu 610041, Sichuan, Peoples R China.

通讯机构：

[Fu, Mingde] S

Sichuan Univ, W China Hosp, Lab Endocrinol & Metab, Chengdu 610041, Sichuan, Peoples R China.

语种：

英文

关键词：

Coronary heart disease;High density lipoprotein subclasses;Diabetic mellitus;Fasting plasma glucose

期刊：

Lipids in Health and Disease

ISSN：

1476-511X

年：

2012

卷：

期：

页码：

1-9

DOI：

10.1186/1476-511X-11-54

基金类别：

Science Foundation of China PostdoctoralChina Postdoctoral Science Foundation [20110491719]

机构署名：

本校为其他机构

院系归属：

化学化工学院

药学与生物科学学院

摘要：

A higher prevalence of coronary heart disease (CHD) in people with diabetes. We investigated the high-density lipoprotein (HDL) subclass profiles and alterations of particle size in CHD patients with diabetes or without diabetes. Plasma HDL subclasses were quantified in CHD by 1-dimensional gel electrophoresis coupled with immunodetection. Although the particle size of HDL tend to small, the mean levels of low density lipoprotein cholesterol(LDL-C) and total cholesterol (TC) have achieved normal or desirable for CHD patients with or without dia...

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High-density lipoprotein subclass and particle size in coronary heart disease patients with or without diabetes

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