Purpose: To investigate the effect of emodin on osteosarcoma cell proliferation and apoptosis.Methods: The osteosarcoma cell proliferation ability was determined by CCK-8, apoptosis level and cell cycle were determined via flow cytometry. Honechst staining was used to determine the ratio of nuclear pyknosis, Western blotting was used to determine the expression of AKT, p-AKT and caspase-3 precursor protein in each group of osteosarcoma cells.Results: Emodin significantly inhibited the MG-63 cell proliferation and promoted the apoptosis of osteosarcoma cells in a dose-dependent manner (p < 0.05...
